Congratulations to members of the Department who have recently had their research findings published. Here’s our round-up of recent publication successes (20/01/20-26/02/20).*
| Title | Date | Authors OR Authors/Contributors | Sub types | Canonical journal title |
| A case of malignant hyperlactaemic acidosis appearing upon treatment with the mono-carboxylase transporter 1 inhibitor AZD3965. | 20/02/2020 | McNeillis R, Greystoke A, Walton J, Bacon C, Keun H, Sitkos A, Petrides G, Leech N, Jenkinson F, Bowron A, Halford S, Plummer R | Journal Article | British Journal of Cancer |
| A meta-analysis of the accuracy of a neuroendocrine tumor mRNA genomic biomarker (NETest) in blood. | 2020-02 | Öberg K, Califano A, Strosberg JR, Ma S, Pape U, Bodei L, Kaltsas G, Toumpanakis C, Goldenring JR, Frilling A, Paulson S | Journal Article, Review | Annals of Oncology |
| A Narrative Review of the Use of Neuromuscular Electrical Stimulation in Individuals With Diabetic Foot Ulceration | 30/01/2020 | Goodall RJ, Langridge B, Lane T, Davies AH, Shalhoub J | Review, Early Access, Journal | International Journal of Lower Extremity Wounds |
| A novel hotspot specific isothermal amplification method for detection of the | 13/02/2020 | Kalofonou M, Malpartida-Cardenas K, Alexandrou G, Rodriguez-Manzano J, Yu L-S, Miscourides N, Allsopp R, L.T. Gleason K, Goddard K, Fernandez-Garcia D, Page K, Georgiou P, Ali S, Coombes RC, Shaw J, Toumazou C | Journal article | Scientific Reports |
| A pragmatic and scalable strategy using mobile technology to promote sustained lifestyle changes to prevent type 2 diabetes in India and the UK: a randomised controlled trial. | 2020-03 | Nanditha A, Thomson H, Susairaj P, Srivanichakorn W, Oliver N, Godsland IF, Majeed A, Darzi A, Satheesh K, Simon M, Raghavan A, Vinitha R, Snehalatha C, Westgate K, Brage S, Sharp SJ, Wareham NJ, Johnston DG, Ramachandran A | Journal Article | Diabetologia |
| A Rare Case of a Small Iliac Aneurysm Causing Iliac Vein Thrombosis. | 24/01/2020 | Papadoulas S, Kakkos SK | Journal Article | European Journal of Vascular and Endovascular Surgery |
| A splice variant of NCOR2, BQ323636.1, confers chemoresistance in breast cancer by altering the activity of NRF2 | 20/02/2020 | Lam E, Leung M, Gong C, Zona S, Yao S | Journal Article | Cancers |
| A systematic review of the role of non-magnified endoscopy for the assessment of H. pylori infection | 01/02/2020 | Glover B, Teare J, Patel N | Review, Journal | Endoscopy International Open |
| An analysis of citations of publications in anaesthesia journals | 03/02/2020 | McHugh UM, Yentis SM | Article, Early Access, Journal | Anaesthesia |
| Artificial intelligence vs. clinicians – a systematic review of the design, reporting standards, and claims of deep learning studies in diagnostic medical imaging | 11/02/2020 | Nagendran M, Chen Y, Lovejoy C, Gordon A, Komorowski M, Harvey H, Topol E, Ioannidis J, Collins G, Maruthappu M | Journal Article | BMJ |
| Baricitinib as potential treatment for 2019-nCoV acute respiratory disease. | 04/02/2020 | Richardson P, Griffin I, Tucker C, Smith D, Oechsle O, Phelan A, Stebbing J | Letter | The Lancet |
| Challenging anatomy. | 08/02/2020 | Kneebone R | Article | The Lancet |
| Clinical Translation of 18F-Fluoropivalate – A PET Tracer for Imaging Short-Chain Fatty Acid Metabolism: Safety, Biodistribution, and Dosimetry in Fed and Fasted Healthy Volunteers | 14/02/2020 | Aboagye E, Dubash S, Keat N, Kozlowski K, Barnes C, Allott L, Brickute D, Hill S, Huiban M, Barwick T, Kenny L | Journal Article | European Journal of Nuclear Medicine and Molecular Imaging |
| Comparison of high-resolution water perfused anorectal manometry with the THD® Anopress anal manometry: a prospective observational study. | 28/01/2020 | Leo CA, Cavazzoni E, Leeuwenburgh MMN, Thomas GP, Dennis A, Bassett P, Hodgkinson JD, Warusavitarne J, Murphy J, Vaizey CJ | Journal Article | Colorectal Disease |
| Correlation between echocardiographic and hemodynamic variables in cardiothoracic intensive care unit | 2020-02 | Tavazzi G, Dammassa V, Corradi F, Klersy C, Patel B, Pires AB, Vazir A, Price S | Article | Journal of Cardiothoracic and Vascular Anesthesia |
| Cyanoacrylate glue embolisation for varicose veins – A novel complication | 28/01/2020 | Langridge BJ, Onida S, Weir J, Moore H, Lane TRA, Davies AH | Article, Early Access, Journal | Phlebology |
| Cytoreductive cryotherapy for newly diagnosed oligometastatic hormone-sensitive prostate cancer. | 19/02/2020 | Connor MJ, Winkler M, Ahmed HU | Letter | Prostate Cancer and Prostatic Diseases |
| Design and Prototyping of a Bio-Inspired Kinematic Sensing Suit for the Shoulder Joint: Precursor to a Multi-DoF Shoulder Exosuit | 01/04/2020 | Varghese RJ, Lo BPL, Yang G-Z | Article, Journal | IEEE Robotics and Automation Letters |
| Effect of Reduced Exposure to Vasopressors on 90-Day Mortality in Older Critically Ill Patients With Vasodilatory Hypotension: A Randomized Clinical Trial. | 12/02/2020 | Lamontagne F, Richards-Belle A, Thomas K, Harrison DA, Sadique MZ, Grieve RD, Camsooksai J, Darnell R, Gordon AC, Henry D, Hudson N, Mason AJ, Saull M, Whitman C, Young JD, Rowan KM, Mouncey PR, 65 trial investigators | Journal Article | JAMA: Journal of the American Medical Association |
| Electrostatic friction displays to enhance touchscreen experience | 25/02/2020 | Haghighi Osgouei R | Chapter | 0 |
| Epilepsy Seizure Prediction on EEG Using Common Spatial Pattern and Convolutional Neural Network | 2020-02 | Zhang Y, Guo Y, Yang P, Chen W, Lo B | Journal Article | IEEE Journal of Biomedical and Health Informatics |
| European Society for Vascular Surgery (ESVS) 2020 Clinical Practice Guidelines on the Management of Vascular Graft and Stent Graft Infections With the Endorsement of the European Association of Nuclear Medicine (EANM). | 30/01/2020 | Chakfé N, Diener H, Lejay A, Assadian O, Berard X, Caillon J, Fourneau I, Glaudemans AWJM, Koncar I, Lindholt J, Melissano G, Saleem BR, Senneville E, Slart RHJA, Szeberin Z, Teebken O, Venermo M, Vermassen F, Wyss TR, Esvs Guidelines Committee, de Borst GJ, Bastos Gonçalves F, Kakkos SK, Kolh P, Tulamo R, Vega de Ceniga M, Document Reviewers, von Allmen RS, van den Berg JC, Debus ES, Koelemay MJW, Linares-Palomino JP, Moneta GLL, Ricco J-B, Wanhainen A | Journal Article | European Journal of Vascular and Endovascular Surgery |
| Evaluating the Trade-offs Men with Localised Prostate Cancer Make Between the Risks and Benefits of Treatments: The COMPARE Study. | 22/01/2020 | Watson V, McCartan N, Krucien N, Abu V, Ikenwilo D, Emberton M, Ahmed HU | Journal Article | The Journal of Urology |
| Evaluation of functional outcomes after a second focal high-intensity focused ultrasonography (HIFU) procedure in men with primary localized, non-metastatic prostate cancer: results from the HIFU Evaluation and Assessment of Treatment (HEAT) registry | 11/02/2020 | Lovegrove CE, Peters M, Guillaumier S, Arya M, Afzal N, Dudderidge T, Hosking-Jervis F, Hindley RJ, Lewi H, McCartan N, Moore CM, Nigam R, Ogden C, Persad R, Virdi J, Winkler M, Emberton M, Ahmed HU, Shah TT, Minhas S | Article, Early Access, Journal | BJU International |
| Exogenous GM1 Ganglioside Attenuates Ketamine-Induced Neurocognitive Impairment in the Developing Rat Brain | 01/02/2020 | Meng C, Yao X-Q, Chang R-J, Wang S-L, Wang X, Ma D-Q, Li Q, Wang X-Y | Article, Journal | Anesthesia and Analgesia |
| Fatty acid amide hydrolase inhibition normalises bladder function and reduces pain through normalising the anandamide/palmitoylethanolamine ratio in the inflamed bladder of rats | 01/02/2020 | Charrua A, Matos R, Oliveira R, Marczylo T, Nagy I, Cruz F | Article, Journal | Naunyn-Schmiedebergs Archives of Pharmacology |
| Focal therapy for localized prostate cancer in the era of routine multi-parametric MRI. | 12/02/2020 | Connor MJ, Gorin MA, Ahmed HU, Nigam R | Journal Article, Review | Prostate Cancer and Prostatic Diseases |
| Frequency of Thrombocytopenia and Heparin-Induced Thrombocytopenia in Patients Receiving Extracorporeal Membrane Oxygenation Compared With Cardiopulmonary Bypass and the Limited Sensitivity of Pretest Probability Score. | 14/02/2020 | Arachchillage DRJ, Laffan M, Khanna S, Vandenbriele C, Kamani F, Passariello M, Rosenberg A, Aw TC, Banya W, Ledot S, Patel BV | Journal Article | Critical Care Medicine |
| Histologic Subtypes and Response to PD-1/PD-L1 Blockade in Advanced Urothelial Cancer: A Retrospective Study. | 23/01/2020 | Miller NJ, Khaki AR, Diamantopoulos LN, Bilen MA, Santos V, Agarwal N, Morales-Barrera R, Devitt M, Nelson A, Hoimes CJ, Shreck E, Assi H, Gartrell BA, Sankin A, Rodriguez-Vida A, Lythgoe M, Pinato DJ, Drakaki A, Joshi M, Velho PI, Hahn N, Liu S, Buznego LA, Duran I, Moses M, Jain J, Murgic J, Barata P, Tripathi A, Zakharia Y, Galsky MD, Sonpavde G, Yu EY, Lyman GH, Grivas P | Journal Article | The Journal of Urology |
| Integrin αvβ6 positron emission tomography imaging in lung cancer patients treated with pulmonary radiotherapy. | 11/02/2020 | Saleem A, Helo Y, Win Z, Dale R, Cook J, Searle GE, Wells P | Journal Article | International Journal of Radiation: Oncology – Biology – Physics |
| Investigating Lower Limb Flap Hemodynamics During Flap Training Regimens and Patient Led Isometric Contraction Protocols: A Prospective Clinical Study | 04/02/2020 | Geoghegan L, Kwasnicki R, Henton J, Hettiaratchy S, Jain A | Journal Article | Plastic and Reconstructive Surgery Global Open |
| Kinetic modelling of acyl glucuronide and glucoside reactivity and development of structure-property relationships. | 19/02/2020 | Bradshaw PR, Richards SE, Wilson ID, Stachulski AV, Lindon JC, Athersuch TJ | Journal Article | Organic and Biomolecular Chemistry |
| Lactic acidosis induces resistance to the pan-Akt inhibitor uprosertib in colon cancer cells | 30/01/2020 | Keun H | Journal Article | British Journal of Cancer |
| Learning from complaints in healthcare: a realist review of academic literature, policy evidence and front-line insights. | 04/02/2020 | van Dael J, Reader TW, Gillespie A, Neves AL, Darzi A, Mayer EK | Journal Article, Review | BMJ Quality and Safety |
| Leptin and fractalkine: Novel subcutaneous cytokines in burn injury | 24/02/2020 | Nagy I, Friston D, Borges Paes Lemes J, Laycock H, Torres-Perez J, Want E, Gyenesei A, Junttila S | Article | Disease Models and Mechanisms |
| Long non-coding RNA dysregulation is a frequent event in non-small cell lung carcinoma pathogenesis. | 05/02/2020 | Acha-Sagredo A, Uko B, Pantazi P, Bediaga NG, Moschandrea C, Rainbow L, Marcus MW, Davies MPA, Field JK, Liloglou T | Journal Article | British Journal of Cancer |
| LPS-Induced Hypotension in Pregnancy: The Effect of Progesterone Supplementation. | 2020-02 | Zöllner J, Howe LG, Edey LF, O’Dea KP, Takata M, Leiper J, Johnson MR | Journal Article | Shock |
| Metabolic biomarkers of squamous cell carcinoma of the aerodigestive tract: a systematic review and quality assessment | 21/01/2020 | Goh YM, Antonowicz S, Boshier P, Hanna G | Review | Oxidative Medicine and Cellular Longevity |
| Metabolism and Effects on Endogenous Metabolism of Paracetamol (Acetaminophen) in a Porcine Model of Liver Failure. | 15/02/2020 | Dargue R, Zia R, Lau C, Nicholls AW, Dare TO, Lee K, Jalan R, Coen M, Wilson ID | Journal Article | Toxicological Sciences |
| Methylnaltrexone for the treatment of opioid-induced constipation and gastrointestinal stasis in intensive care patients. Results from the MOTION trial. | 03/02/2020 | Patel PB, Brett SJ, O’Callaghan D, Anjum A, Cross M, Warwick J, Gordon AC | Journal Article | Intensive Care Medicine |
| Monitoring spatiotemporal changes in chaperone-mediated autophagy in vivo. | 31/01/2020 | Dong S, Aguirre-Hernandez C, Scrivo A, Eliscovich C, Arias E, Bravo-Cordero JJ, Cuervo AM | Journal Article | Nature Communications |
| Morphology and Computational Fluid Dynamics Support a Novel Classification of Common Iliac Aneurysms. | 22/01/2020 | Parker LP, Powell JT, Kelsey LJ, Venermo M, Koncar I, Norman PE, Doyle BJ | Journal Article | European Journal of Vascular and Endovascular Surgery |
| MRI-guided ultrafocal salvage high-dose-rate brachytherapy for localized radiorecurrent prostate cancer: updated results of 50 patients. | 29/01/2020 | van Son MJ, Peters M, Moerland MA, Lagendijk JJW, Eppinga WSC, Shah TT, Ahmed HU, van der Voort van Zyp JRN | Journal Article | International Journal of Radiation: Oncology – Biology – Physics |
| NET-02 trial protocol: a multicentre, randomised, parallel group, open-label, phase II, single-stage selection trial of liposomal irinotecan (nal-IRI) and 5-fluorouracil (5-FU)/folinic acid or docetaxel as second-line therapy in patients with progressive poorly differentiated extrapulmonary neuroendocrine carcinoma (NEC) | 05/02/2020 | Craig Z, Swain J, Batman E, Wadsley J, Reed N, Faluyi O, Cave J, Sharma R, Chau I, Wall L, Lamarca A, Hubner R, Mansoor W, Sarker D, Meyer T, Cairns DA, Howard H, Valle JW, McNamara MG | Journal Article | BMJ Open |
| NHS data: Maximising its impact on the health and wealth of the United Kingdom | 05/02/2020 | Ghafur S, Fontana G, Halligan J, O’Shaughnessy J, Darzi A | Report | |
| NK cells augment oncolytic adenovirus cytotoxicity in ovarian cancer | 10/02/2020 | McNeish I, Ennis D, McNamara S, Spiliopoulou P, Nautiyal J | Journal Article | Molecular Therapy – Oncolytics |
| Observer agreement for small bowel ultrasound in Crohn’s disease: results from the METRIC trial. | 10/02/2020 | Bhatnagar G, Quinn L, Higginson A, Plumb A, Halligan S, Tolan D, Lapham R, Mallett S, Taylor SA, METRIC study investigators | Journal Article | Abdominal Radiology |
| Oncologist-led BRCA ‘mainstreaming’ in the ovarian cancer clinic: A study of 255 patients and its impact on their management | 08/02/2020 | McNeish I, Krell J, Gabra H | Journal Article | Scientific Reports |
| Patient advocacy in head and neck cancer: Realities, challenges and the role of the multi-disciplinary team. | 23/01/2020 | Dawson C, Roe J, Starmer H, Brady G, Nund R, Coffey M, Govender R, Patterson JM, Nankivell P, Topping A, Sharma N, Parmar S, Elkington C, Merrit M, Stanbury D, Pracy P | Editorial | Clinical Otolaryngology |
| Phosphorylation independent eIF4E translational reprogramming of selective mRNAs determines tamoxifen resistance in breast cancer. | 17/02/2020 | Gong C, Tsoi H, Mok KC, Cheung J, Man EPS, Fujino K, Wong A, Lam EWF, Khoo U-S | Journal Article | Oncogene |
| Polycomb-mediated repression of EphrinA5 promotes growth and invasion of glioblastoma | 27/01/2020 | Ricci B, Millner TO, Pomella N, Zhang X, Guglielmi L, Badodi S, Ceric D, Gemma C, Cognolato E, Zhang Y, Brandner S, Barnes MR, Marino S | Article, Early Access, Journal | Oncogene |
| Postoperative chemotherapy improves survival in patients with resected high-risk stage II colorectal cancer: results of a systematic review and meta-analysis. | 30/01/2020 | Simillis C, Singh HKSI, Afxentiou T, Mills S, Warren OJ, Smith JJ, Riddle P, Adamina M, Cunningham D, Tekkis PP | Journal Article, Review | Colorectal Disease |
| Projected impact of the Portuguese sugar-sweetened beverages tax on obesity incidence across different age groups: a modelling study | 24/01/2020 | Goiana-da-Silva F, Severo M, Cruz-E-Silva D, Gregório MJ, Allen L, Muc M, Morais Nunes A, Torres D, Miraldo M, Ashrafian H, Rito A, Wickramasinghe K, Breda J, Darzi A, Araújo F, Lopes C | Journal Article | PLoS Medicine |
| Quantitative proteomic analysis of the central amygdala in neuropathic pain model rats. | 12/02/2020 | Karu K, Swanwick RS, Novejarque-Gadea A, Antunes-Martins A, Thomas B, Yoshimi E, Foster W, Fang M, McMahon SB, Bennett DL, Rice AS, Okuse K | Journal Article | Journal of Proteome Research |
| Rathke’s cleft cysts following transsphenoidal surgery: long-term outcomes and development of an optimal follow-up strategy. | 25/01/2020 | Marcus HJ, Borg A, Hussein Z, Jaunmuktane Z, Baldeweg SE, Grieve J, Dorward NL | Journal Article | Acta Neurochirurgica: the European journal of neurosurgery |
| Robust belief state space representation for statistical dialogue managers using deep autoencoders | 20/02/2020 | Lygerakis F, Diakoloulas V, Lagoudakis M, Kotti M | Proceedings Paper | |
| Safety and efficacy of laparoscopic near-total colectomy and ileo-distal sigmoid anastomosis as a modification of total colectomy and ileorectal anastomosis for prophylactic surgery in patients with adenomatous polyposis syndromes: a comparative study | 28/01/2020 | Anele CC, Nachiappan S, Sinha A, Cuthill V, Jenkins JT, Clark SK, Latchford A, Faiz OD | Article, Early Access, Journal | Colorectal Disease |
| Safety of hospital discharge before return of bowel function after elective colorectal surgery | 24/01/2020 | Chapman SJ | Article, Early Access, Journal | British Journal of Surgery |
| Soft Pneumatic Actuator for Rendering Anal Sphincter Tone. | 21/01/2020 | Haghighi Osgouei R, Marechal L, Kontovounisios C, Bello F | Journal Article | IEEE Transactions on Haptics |
| Study protocol for a comparative diagnostic accuracy study of bedside tests used to detect arterial disease in diabetes: TEsting for Arterial disease in Ddiabetes (TrEAD) study. | 05/02/2020 | Normahani P, Poushpas S, Alaa M, Bravis V, Aslam M, Jaffer U | Journal Article | BMJ Open |
| Taking the Pressure off the Patient – Understanding Digital Rectal Examinations on a Real Subject. | 05/02/2020 | Granados A, Cox S, Low-Beer N, Higham J, Kneebone R, Bello F | Journal Article | IEEE Transactions on Biomedical Engineering |
| The Applications of Deep Learning in Plastic and Reconstructive Surgery: Protocol of a Systematic Review | 20/02/2020 | Khajuria A, Mantelakis A | Journal Article | Systematic Reviews |
| The World Is Not Enough: How Can “Big Data” Inform Guidelines for Elective AAA Repair? | 05/02/2020 | Lyons O, Powell JT | Journal Article | European Journal of Vascular and Endovascular Surgery |
| Tracking physical activity using smart phone apps: assessing the ability of a current app and systematically collecting patient recommendations for future development. | 03/02/2020 | Murphy J, Uttamlal T, Schmidtke KA, Vlaev I, Taylor D, Ahmad M, Alsters S, Purkayastha P, Scholtz S, Ramezani R, Ahmed AR, Chahal H, Darzi A, Blakemore AIF | Journal Article | BMC Medical Informatics and Decision Making |
| Transoral robotic surgery for recurrent cancers of the upper aerodigestive tract-Systematic review and meta-analysis. | 18/02/2020 | Hardman J, Liu Z, Brady G, Roe J, Kerawala C, Riva F, Clarke P, Kim D, Bhide S, Nutting C, Harrington K, Paleri V | Journal Article, Review | Head and Neck: journal for the sciences and specialities of the head and neck |
| Trends in peripheral arterial disease incidence and mortality in EU15+ countries 1990-2017. | 03/02/2020 | Goodall R, Salciccioli JD, Davies AH, Marshall D, Shalhoub J | Article | European Journal of Preventive Cardiology |
| Understanding the Role of Comparative Clinical Studies in the Development of Oncology Biosimilars. | 14/02/2020 | Stebbing J, Mainwaring PN, Curigliano G, Pegram M, Latymer M, Bair AH, Rugo HS | Journal Article | Journal of Clinical Oncology |
| Visual behaviour in robotic surgery-Demonstrating the validity of the simulated environment | 03/02/2020 | Dilley J, Singh H, Pratt P, Omar I, Darzi A, Mayer E | Article, Early Access, Journal | International Journal of Medical Robotics and Computer Assisted Surgery |
| What are the benefits and risks of sharing patients’ diagnostic radiological images with them? A cross-sectional study of the perceptions of patients and clinicians in the UK. | 22/01/2020 | Cox WAS, Cavenagh P, Bello F | Journal Article | BMJ Open |
*The mysterious case of the missing publication: a disclaimer
To ensure the quality and accuracy of the information published on this blog, we source our data directly from Symplectic. Our reports are generated on a fortnightly basis, which means there may be a delay in publicising some publications.