Developing the Coronavirus Vaccine

Fighting Covid-19 at Imperial

I visited the Section of Immunology of Infection where Professor Robin Shattock’s team are developing a vaccine for the Coronavirus.

Image © Thomas Angus, Imperial College London
Professor Robin Shattock blocks the path of your pandemic with his vaccine team.

Image © Thomas Angus, Imperial College London  

Robin with research technician Leon Mcfarlane.

Image © Thomas Angus, Imperial College London  

Senior Research Fellow Dr Paul McKay was instrumental in the development of the Vaccine, working here in the lab space created exclusively to do battle with Coronavirus

Image © Thomas Angus, Imperial College London  

Paul at the fume hood.

Image © Thomas Angus, Imperial College London 

The plate culture Paul used to develop the vaccine.

Image © Thomas Angus, Imperial College London 

Senior Research Fellow Dr Paul McKay.

Imperial College London 

Map of the COVID-19 plasmid – the plasmid is used to produce the RNA replicon using an in vitro transcription reaction.

Image © Thomas Angus, Imperial College London  

The vaccine ‘broth’

Image © Thomas Angus, Imperial College London  

The contents of these very cold boxes could potentially be very useful.

Image © Thomas Angus, Imperial College London 

The Coronavirus vaccine, human trials expected to begin in April.

Image © Thomas Angus, Imperial College London 

Karnyart Samnuan is a PhD Student also working in the lab. “My research focuses on the optimization of the production and function of self-amplifying RNA vaccines in order to improve immunogenicity and cost-effectiveness. The main goals are to enable local production of RNA vaccines across the world as well as to develop a platform that can be used to rapidly respond to outbreaks.”

RNA gel showing the self-amplifying replicon RNA for the COVID-19 vaccine

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