Blog posts

Banking on brains: the quest for new methods of treatment for Parkinson’s

Parkinson's

For World Parkinson’s Day, Ben Tilley highlights how brain tissue donated to Imperial’s Tissue Bank is instrumental in finding new methods of treatment for Parkinson’s. 


My personal journey with Parkinson’s disease (PD) research started six years ago. It was the summer of 2012, and while enjoying the London Olympics and preparing myself to start Medical School at Imperial College London, my father was developing symptoms of PD. When the diagnosis was made I knew what my career goal would be; I had to study this disease and I had no ambitions other than to become a neurologist in the future. (more…)

Universal Health Coverage in the United Kingdom: past, present and future

NHS staff with a patient at Charing Cross Hospital
NHS staff with a patient at Charing Cross Hospital

On World Health Day, Professor Azeem Majeed takes a look at the past, present and future of the NHS.


In 2018, the United Kingdom’s National Health Service (NHS) celebrates its 70th anniversary. With the creation of the NHS in 1948, universal health coverage was finally implemented in the United Kingdom, with the NHS replacing the previous patchy health coverage schemes that had left many people with limited access to health services. All residents of the United Kingdom were given the right to register with a general practitioner, who was responsible for both providing primary care services and organizing referrals for specialist care. (more…)

Could the EndoBarrier be the next weapon of mass reduction?

Endobarrier

In this post, Dr Aruchuna Mohanaruban tackles the most asked questions about the EndoBarrier – a medical device for the treatment of type 2 diabetes and obesity.


UK obesity rates have continued to rise at an alarming rate, with figures higher than any other developed nation. Strongly associated with obesity is the increased susceptibility to developing type 2 diabetes (T2DM) which currently affects 3.2 million of the UK population. Bariatric surgery – a type of surgery aimed at inducing weight loss – usually by altering the stomach and/or intestines has revolutionised the treatment of these conditions and can lead to a 60% remission in diabetes. However, with demand for this type of surgery outstripping supply, there is a greater need to develop non-surgical alternatives to combat the ever-rising obesity and diabetes epidemic. (more…)

Do we need to think differently about COPD?

COPD
The internal structure of the lungs by Dave Farnham (CC BY 4.0)

Ann Morgan, a PhD student at the National Heart and Lung Institute, gives us her thoughts on why smoking isn’t the only culprit behind the rise in COPD. 


The traditional view of COPD (chronic obstructive pulmonary disease) is that it is a self-inflicted disease caused by smoking. However, it is increasingly likely that this description is something of an oversimplification. While still very much associated with smoking, clinicians and researchers alike are getting to grips with the reality that COPD is a more complex and heterogeneous disease than previously thought. We are also becoming more aware of the fact that it is a disease which rarely occurs in isolation. The vast majority of people who present with COPD have at least one other co-existing disease or condition, and around 50% have four or more accompanying chronic diseases or ‘comorbidities’. (more…)

Updating parents on neonatal units: “You can also log in to the app!”

parents with babies in neonatal care

Dr Susanna Sakonidou writes on how the BUDS project is improving the experience for parents of babies in neonatal care with an app.


Alarms going off, doctors and nurses rushing across the ward, parents desperately trying to catch someone’s eye to get an update. The reality of having babies in neonatal care is undoubtedly traumatic for parents. As high as 35% of them can develop symptoms of post-traumatic stress disorder (1), which can in turn interfere with the process of baby-parent bonding (2).

Having a baby that requires neonatal care is more common than one might think. One in eight babies born in the UK are admitted to a neonatal unit and surveys show that parents struggle to adjust to this unfamiliar environment. Getting verbal updates about their babies is difficult, given how busy staff is dealing with emergencies on the unit. As a result, parents frequently feel excluded from their babies’ care. (more…)

SheNote Speaker: addressing the gender imbalance in science

SheNote Speaker

This International Women’s Day, Dr Mike Cox On is launching SheNote Speaker to help address the gender imbalance in science.


Dr Elisabeth Bik is a microbiome researcher and science editor who runs Microbiome Digest, a blog that’s updated daily and highlights microbiome literature worth reading. In 2016 she asked scientists in the field to nominate their favourite women microbiome researchers in order to improve the visibility of women in the field. This developed to become an actively updated database of experts that’s easily searchable by research interest in microbiome science – Women In Microbiome Research. Dr Bik explains the motivation for establishing the list clearly on her site, but one of the major driving forces was the lack of women as keynote speakers, panel members or chairs at conferences. (more…)

Rare diseases: the hidden priority of scientific research

For Rare Disease Day, Professors Uta Griesenbach and Eric Alton tell us why rare diseases are the hidden priority of scientific research.


A rare disease, also known as an orphan disease, affects by definition less than five in 10,000 (or 0.05%) of the general population.

Hence the question arises: why a disease as rare as 0.05% of the population presents a good investment of research funding? We think the answer is simple and importantly the math adds up. Here are some facts, based on raredisease.org.uk: (more…)

Making the leap from PhD to postdoc

Following the annual Rising Scientist Day, Drs Myrsini Kaforou, Alex Thompson and Claire Byrne recount their experiences of becoming fully-fledged early career researchers and share their best advice for prospective postdocs.


The annual Rising Scientist Day at Imperial’s Hammersmith Campus offers PhD students the chance to share their research both with their peers, and a more general audience. In addition to poster presentations and networking opportunities, the showcase featured talks from those who had successfully made the transition from PhD to postdoc. (more…)

Encephalitis: the rare disease with a million implications

 

22 February is World Encephalitis Day. Founded by The Encephalitis Society four years ago, it aims to help raise awareness of the disease on an international scale.


In a nutshell, encephalitis refers to the inflammation of the brain. Up until recently, it was thought that encephalitis was simply either a viral or bacterial infection. However, in 2005, research described a new version of the disease: auto-immune or ‘anti-NMDAR encephalitis’, which is caused by antibodies that attack the brain tissue. In all its forms, encephalitis is incredibly rare: herpes simplex encephalitis (HSE), for instance, affects approximately one in 1,000,000 children. Although there are clear treatment routes available, viral encephalitis is incredibly destructive. The virus can cause irreversible damage in the brain, which will continue to impact upon a patient’s quality of life well after their short-term recovery from the disease itself. (more…)

Cracking the genetic code of cardiomyopathy in Egyptians

In the post, PhD student Mona Allouba, calls for a better understanding of the genetics of Egyptians in a bid for personalised treatments for cardiomyopathy patients


Over the past decade, several institutions in Egypt have been making huge scientific progress that is steadily reaching worldwide recognition. It is under these circumstances that I have been fortunate to join the Magdi Yacoub Foundation (MYF), which is recognised as one of Egypt’s most prominent charity organisations. The Aswan Heart Centre – located along the banks of the Nile in Aswan – is an integral part of MYF, offering state-of-the-art medical services for the underprivileged. It focuses on expanding the research on heart disease across the Middle East and beyond to contribute to the world’s scientific knowledge. (more…)