PhD student Philippa May reflects on being a scientist in the field blood cancer, from working in a leukaemia diagnostic laboratory to a research laboratory.
For the last 10 years I have been a clinical scientist in genetics working across various London NHS Trusts. Whilst I loved diagnostics, last year I left my job to complete my PhD. I worked in a part of life sciences called cytogenetics. This meant when a patient was diagnosed with blood cancer, I would analyse their chromosomes – the structures into which DNA is organised – from their blood or bone marrow to look for specific abnormalities. For some patients, this can lead to a definitive diagnosis. For others a refined prognosis, and in some, it’s simply a way of monitoring how well the patient’s leukaemia is responding to their treatment. (more…)
In the post, Neil Dufton asks: How can we bring together imaging technology, art and philosophy to shape scientific research?
When we think of vascular health we are often guilty of presuming that we are primarily discussing the heart. Clearly the heart has a major role to play in regulating your blood flow; once our blood has exited the heart it must supply nutrients to every organ of our body and back to the heart in a cycle that takes about one minute. Any hindrance from a cholesterol-blocked artery or blood clot can have catastrophic results – however by the time we reach retirement our circulation will have exceeded 30 million laps around the body! This incredible feat is made possible by our blood vessels that not only form a vast network during your development in the womb, but are also constantly growing and remodelling throughout our life time. Our Vascular Science research group at the National Heart and Lung Institute is particularly interested in endothelial cells – the cells that line every blood vessel in our body. We want to understand how they work together to grow and form new vessels (a process called angiogenesis), as well as how they maintain these structures in response to injury and disease. (more…)
Here, Vinay Mandagere a medical student, reflects on his journey through medical school, from initial rejection to researching TB.
It was extremely challenging for me to stare back at the four rejections that faced me. Four rejections from four separate medical schools. Four independent reviewers telling me I was not to be a doctor. I had to endure seemingly unending encouragements and sympathies from friends and family. Their attempts were well-meaning, but often repetitive. My particular favourite was “I believe Edward Jenner didn’t get into medical school the first time round”. This, of course, was a complete fabrication. I think I always had this naïve cockiness about me, an artless assumption that I had the necessary experiences to stroll into medical school. Perhaps rejection had a subduing effect on my ego, though, I probably would presume most of those who know me would thoroughly disagree.
Nevertheless, it occurred to me that I had a year to convince the doctors of now that I could be a doctor of the future. But then I thought again. I had an entire year to do what I wanted. I found myself avoiding medical work of any sort, and take up a job in a bakery. I normally stop here when I want to impress people, to give the impression that I mastered the art of conjuring delicious, enticing pastries. In fact, it is due to my semi-duplicitous nature that many people still think of me as a great baker. But I’m not. In reality, my primary role was to serve customers, clean and wash up (as well as outline the difference between spelt bread and gluten-free bread: a distinction I still don’t understand to this day). It was an enjoyable job, and it provided me with some money to fuel some travelling later on. Moreover, I had the blessing of taking home two full bags of artisan breads untouched by the day’s customers — a perk which became more and more hedonistic as the year went on. (more…)
For World Water Week, Dr Anna Phillips from the Schistosomiasis Control Initiative explains clean water is crucial to the elimination of schistosomiasis.
Can you imagine life without access to clean water? Unfortunately for 663 million people this is a reality. That’s nearly one in ten people worldwide living without a safe water supply close to home, spending hours queuing or trekking to distant sources and coping with the health impacts of using contaminated water. SIWI’s (Stockholm International Water Institute) World Water Week, is a pertinent time to reflect on important research carried out by the Schistosomiasis Control Initiative (SCI), a non-profit initiative based at Imperial College London, which highlights why access to clean water is so important to human health. (more…)
Jennifer Shelton from the School of Public Health reflects on a recent field trip to Taiwan which involved studying amphibians.
Close your eyes and imagine the high-pitched shrieking of cicadas unified in a crescendo of noise from the treeline. Fireflies blinking their fluorescence through the undergrowth. Bats swooping silently overhead, rustling your hair with their wing beats. Trekking across steep hillsides of wasabi plants during a rainstorm. Not the average working week of a researcher in the School of Public Health, but just some of the sights and sounds I was fortunate to experience when I visited Taiwan in May as a National Geographic Young Explorer. (more…)
Originally published on the Imperial College Healthcare NHS Trust blog, here clinical nurse specialist Venetia Wynter-Blyth explains how the programme helps patients adopt the good habits needed to aid their recovery.
All types of surgery require preparation and, afterwards, recovery time. But according to the oesophago-gastric cancer team at Imperial College Healthcare NHS Trust, undergoing major surgery is like running a marathon. The PREPARE for Surgery programme, designed by the team, ‘trains’ patients for surgery based on their individual needs. It looks at different factors important to focus on before and after a procedure, including physical activity, diet, psychological wellbeing and medication management. (more…)
Dr Susan Young, a clinical psychologist and author, is turning conventional ADHD treatment on its head with a series of programmes for children and adults.
I started working with young people with attention deficit hyperactivity disorder 25 years ago. Over the years, our knowledge and understanding of ADHD has come a long way – mostly down to scientific research – taking the condition from a relatively unheard one to a household one. Too often, we associate ADHD with children, however it’s now recognised to be a lifetime condition with many undiagnosed adults continuing to experience symptoms throughout their lives, despite the abundance of international guidelines on the assessment, treatment and management of ADHD. With many young people reaching adulthood with undiagnosed ADHD, or even misdiagnosed, they will not receive the optimal treatment for their symptoms and associated problems. Unfortunately, many will not reach their potential, and for some, they feel their future is bleak. (more…)
PhD student Dr Ishita Marwah writes about her personal take on tuberculosis – a disease that continues to be a global issue.
I was always a sickly child – when I was eleven years old, doctors injected my forearm with tuberculin in order to check whether my immune system raised a response to the bits and bobs of dead tuberculosis (TB) bacteria in it. If it did, it meant my immune system had already been prodded into battling TB, that is, it had previously encountered or was currently encountering an infection with TB bacteria. The injection site swelled like a furious bee sting, the doctors decided TB was the root cause of all my troubles, and I was intensely medicated for the next six months. My symptoms improved, and I have since evolved (visibly even!) towards the hale and hearty end of the healthiness spectrum. (more…)
From gluten-free to detox diets, Dr Anusha Seneviratne dissects the scientific evidence (or lack of) behind eccentric diets.
Magazines and newspapers are full of so-called ‘tips’ or ‘advice’ for the image conscious, detailing extreme diets followed by the rich and famous to achieve dramatic weight loss, or new diets apparently supported by the latest scientific research. One example is the gluten-free diet, made fashionable particularly in the sporting world by former world number one tennis player Novak Djokovic (1). Having had a reputation for being physically weaker than his rivals, Djokovic was eventually diagnosed with coeliac disease and the resulting gluten intolerance. Eliminating gluten from his diet transformed his career. (more…)