Category: Disease

FEAST – five years on

By Professor Kathryn Maitland, Director of the IGHI Centre of African Research and Engagement. 

First published by the Hippocratic Post on 22/8/16.

‘Back in 2011, my research team published the results of the largest trial of critically ill children ever undertaken in Africa (FEAST trial), a trial that examined fluid resuscitation strategies in children with severe febrile illnesses (including malaria and bacterial sepsis). Contrary to expectation, the trial showed that fluid boluses were associated with an increased mortality compared to no-bolus (control), the greatest effect was in children with the most severe forms of shock. We were delighted when the FEAST trial won the prestigious 2011 BMJ Research Paper of the Year award and expected that doctors around the world would sit up and take notice – and guidelines for management of children suffering from shock due to sepsis would change.

Towards Eliminating Schistosomiasis in Africa – A Multi-Disciplinary Effort

By Dr Michael Templeton, Reader in Public Health Engineering, Department of Civil and Environmental Engineering, Imperial College London

Wednesday, May 25th 2016 marks Africa Day, the 53rd anniversary of the founding of the Organisation of African Unity, the forerunner of the African Union. There have been so many wonderful developments in Africa in the last 53 years, but sadly the quality of life of many of the poorest people in Africa continues to be limited by the burden of a group of debilitating diseases known collectively as neglected tropical diseases (NTDs), which have afflicted millions of Africans since ancient times.

World Malaria Day 2016: Africa, children and malaria

By Professor Kathryn Maitland, Professor of Tropical Paediatric Infectious Diseases and Director of IGHI’s new Centre for African Research and Engagement (ICCARE).

Across large parts of sub-Saharan Africa the major rains have got underway; which typically means that in a few weeks, hospitals will witness a seasonal upsurge of admissions into the children’s wards. Most of these will be children suffering a new bout of malaria, with around ten percent of these malaria admissions having life-threatening complications such a coma (cerebral malaria), severe anaemia (requiring urgent life-saving transfusion) and rapid breathing (to try to compensate for the build up of acids in their bodies).

World Toilet Day 2015: Making sanitation sustainable and safe

By Dr Michael Templeton, Reader in Public Health Engineering

Today, Thursday 19th November, is World Toilet Day. Sadly, it is estimated that 2.5 billion people around the world still lack access to an adequate toilet. Many others rely on only basic pit latrines which eventually fill up and can become unsanitary. Many countries failed to meet their Millennium Development Goal target for access to improved sanitation, and the recently stated Sustainable Development Goals continue to emphasise improving sanitation as a key objective towards global development.

Research at Imperial College London by the group of Dr Michael Templeton in the Environmental and Water Resource Engineering section of the Department of Civil and Environmental Engineering is investigating ways to make sanitation more sustainable and safer.

World Mosquito Day 2015: The burden of Malaria today

By Alison Reynolds and Dr Thomas Churcher from Imperial’s Malaria Modelling Research Group

World Mosquito Day (20th August) commemorates the discovery that mosquitoes transmit the parasite that causes malaria, made in 1897 by British doctor Ronald Ross.

A hundred and eighteen years later this transmission still continues, to some extent unabated. There have been huge successes in malaria control, most notably in recent years, though a child still dies every minute[1] from a disease which continues to ravage large swathes of Africa and Asia. Importantly these deaths are completely avoidable, as we have effective tools to treat malaria and stop people dying.

Tackling HIV associated Tuberculosis this World AIDS Day

By Professor Robert Wilkinson, Wellcome Trust Senior Fellow in Clinical Tropical Medicine, Director of the University of Cape Town Clinical Infectious Diseases Research Initiative (CIDRI) and Professor in Infectious Diseases at Imperial College London

Today, 1st December, is World AIDS Day, an opportunity for people worldwide to unite in the fight against HIV, show their support for people living with the disease and to commemorate people who have died. World AIDS Day was the first ever global health day and the first one was held in 1988.

According to the World Health Organisation (WHO), since the beginning of the epidemic, almost 78 million people have been infected with the HIV virus and about 39 million people have died of HIV.

WaterAid UK / International World Toilet Day

Today 36 prominent international health and development experts including representatives from WaterAid, The World Medical Association, the Institute of Global Health Innovation, Amref Health Africa,  Bangladesh Medical Association, British Medical Association, Commonwealth Medical Association, Global Health Council, Indian Medical Association, International Confederation of Midwifes, Nigerian Medical Association, and the Royal College of General Practitioners amongst many others, have called for an end to a crisis that has claimed the lives of over 10 million children under the age of five since the year 2000.  

In an Open letter to the Secretary-General of the United Nations, Ban Ki Moon, the signatories, representing over 620,000 health professionals globally, highlight the desperate waste of life caused by people not having access to a basic toilet.